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Graduate Students

Rakesh Mengji

PROJECT ASSISTANT  -II, ID NO:-11004

Email: rakesh.iict15@gmail.com

Phone: 9966619159 / 9000940650

 

I completed my schooling at  Zilla Parishat Boys  High School, Kodangal. During my school I was in NCC (National Candidate Crops) and I qualified A-certificate and achived a silver medal in shooting, and partiespated cultural activities at NCC camp.

I completed my intermediate at Govt Junior college Kodangal (2007-09) with Bi.P.C group. I completed Msc.  5 Years Integrated Chemistry at UNIVERSITY OF PG COLLEGE, PALAMURU UNIVERSITY (2019-14) during my PG I was in NSS (National Service Scheme) I got certificate of merit.  And I started NGO called HRUDAYA ORGANISATION with Mr. ARJUN KUMAR, MBA faculty   at UNIVERSITY OF PG COLLEGE, PALAMURU UNIVERSITY , MAHABOOB  NAGAR. and with my classmates G. DEEPTHI REDDY, B. ANUSHA, M. SOMNATH. We conducted blood donation camp and health camp at Bandameedipally village, Mahaboobnagar and also conducted eye & dental camps at Zamistapur  village, mahaboobnagar.

I started my research carrier as project tranie under the guidance of Dr. P.RADHA KRISHNA (chief scientist) OBC Division  CSIR-IICT HYDERABAD  for 6 months and followed by working  as Project Assistant- II  under the guidance of Dr. B. V. SUBBA REDDY (senior principal scientist) NPC Division CSIR-IICT HYDERABAD  for 18 months. 

 

Currently I am working as Project Assistant- II  under the guidance of Dr Avijit Jana.

 

RESEARCH INTREST: Biomaterials chemistry

Publications:

1. Biswajit Roy, Rakesh Mengji, Samrat Roy, Bipul Pal, Avijit Jana* and N. D. Pradeep Singh* NIR-Responsive Lysosomotropic Phototrigger: An “AIE + ESIPT” Active Naphthalene-Based Single-Component Photoresponsive Nanocarrier with Two-Photon Uncaging and Real-Time Monitoring Ability, ACS Appl. Mater. Interfaces, 2022, DOI: 10.1021/acsami.1c19022

 

2. Amrita Paul,   Rakesh Mengji,   Manoranjan Bera,   Mamata Ojha,   Avijit Jana*  and  Pradeep N.D. Singh*,  Mitochondria-localized In Situ Generation of Rhodamine Photocage with Fluorescence Turn-On Enabling Cancer Cell-Specific Drug Delivery Triggered by Green Light, Chem. Comm. 2020, doi.org/10.1039/D0CC03524F.

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3. Amrita Chaudhuri, Rakesh Mengji, Yarra Venkatesh, Avijit Jana,* and N. D. Pradeep Singh,* Improved Tumor-specific Therapeutic Strategy by Spatio-temporal in situ Formation of Cu(II)-complex, Leading to Prompt Cell Apoptosis via Photoactivation of the Prodrug, Chem. Comm. 2020, doi.org/10.1039/D0CC00667J.

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4. Rakesh Mengji, Chiranjit Acharya, Vangala Venugopal, Avijit Jana,* A Lysosome Specific Near-Infrared Fluorescent Probe for the in vitro Cancer Cell Detection and Non-Invasive in vivo Imaging, Chem. Comm. 2019, 55, 14182-14185.

 

5. Sandipan Biswas, Rakesh Mengji, Shrabani Barman, Venugopal Vangala, Avijit Jana* and N. D. Pradeep Singh,* ‘AIE + ESIPT’ Assisted Photorelease: Fluorescent Organic Nanoparticles for Dual Anticancer Drug Delivery with Real-Time Monitoring Ability, Chem. Comm. 2018, 54, 168-171.

 

6. Moumita Gangopadhyay,  Rakesh Mengji,  Amrita Paul,  Venkatesh Yarra ,  Vangala Venugopal,  Avijit Jana*  and  Pradeep N.D. Singh,* Redox-responsive Xanthene-coumarin-chlorambucil-based FRET-guided theranostics for “activatable” combination therapy with real-time monitoring, Chem. Comm. 2017, 53, 9109-9112.

 

7. Amrita Paul, Rakesh Mengji, Olive Abraham Chandy, Surajit Nandi, Manoranjan Bera, Avijit Jana,*  Anakuthil Anoop*  and N. D. Pradeep Singh,* ESIPT-Induced Fluorescent o-Hydroxycinnamate: Self-Monitoring Phototrigger for Prompt Image-Guided Uncaging of Alcohols, Org. Biomol. Chem. 2017, 15, 8544-8552.

Project Assistants

Postdoctoral Fellow

 

Dr. Chiranjit Acharya

 

ID No.

E-mail: cacharya1984@gmail.com 

Educational Details:

Dr. Acharya did his BSc from Vidyasagar University in 2005 and MSc in 2007 from the same University. Then he moved to CSIR-Indian Institute of Chemical Biology to pursue his doctorate study under the supervision of Dr. P. Jaisankar. During his PhD tenure he got the opportunity to work with Prof. Hiroshi Sugiyama at Kyoto University, Japan as a PhD internship fellow. After completing his PhD on the topic entitled “Synthetic studies on chiral and achiral organic compounds using metal and biocatalysts” he was appointed as research associate in the same lab in 2015. During his doctoral studies he has publish five articles in internationally reputed peer reviewed journals. One of those article has been accepted as cover page article of a journal. In 2017 he was awarded by the CSIR-RA fellowship followed by N-PDF. Currently, he is continuing his postdoctoral research as N-PDF at CSIR-Indian Institute of Chemical Biology with Dr. Avijit Jana in the field of drug delivery.

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Awards/Honors

  • JRF-UGC

  • CSIR-RA

  • N-PDF

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Publications

  1. Rakesh Mengji, Chiranjit Acharya, Vangala Venugopal, Avijit Jana,* Lysosome Specific Near-Infrared Fluorescent Probe for the in vitro Cancer Cell Detection and Non-Invasive in vivo Imaging, Chem. Comm. 2019, DOI:10.1039/C9CC07322A.

  2. Chiranjit Acharya, Madhumita Mandal, Trina Dutta, Anil Kumar Ghosh, Parasuraman Jaisankar,* Enzyme from Daucus carota root catalyzed asymmetric cross aldol reactions. Tetrahedron Lett. 2016, 57, 4382-4385. Appeared as cover page article

  3. Chiranjit Acharya, Sourav Saha, Parasuraman Jaisankar, Hemanta Kumar Majumder, A novel spirooxindole derivative inhibits the growth of Leishmania donovani parasite both in vitro and in vivo by targeting type IB topoisomerase. Antimicrob. Agents Chemother. 2016, 60, 6281-6293.

  4. Soyoung Park, Izumi Okamura, Sohei Sakashita, Ji ye Yum, Chiranjit Acharya, Li Gao, and Hiroshi Sugiyama, Development of DNA Metalloenzymes Using a Rational Design Approach and Application in the Asymmetric Diels–Alder Reaction. ACS Catalysis 2015, 5, 4708.

  5. Sanjit K. Mahato, Rafique Ul Islam, Chiranjit Acharya, Michael J. Witcomb and Kaushik Mallick, Polymer-Stabilized Palladium Nanoparticles for the Chemoselective Transfer Hydrogenation of α, β-Unsaturated Carbonyls: Single-Step Bottom-Up Approach. ChemCatChem. 2014, 6, 1419.

  6. Chiranjit Acharya, Sumit Dey and Parasuraman Jaisankar, Indium trichloride catalyzed multicomponent one pot route to 1-hydroxymethyl, 3-aminomethyl indoles. Tetrahedron Lett. 2012, 53, 5548.

Alumni

Summer Research Trainee 

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Padmasree Chalamalasetti                                                                              

Terasa M. Tejaswani

 

P. Sivakumar                                           

Graduate Student 
Dr. Venugopal Vangala

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